Telomere, the
section of DNA base pairs at the end of the chromosome,
functions as a disposable buffer (for more on
DNA see a previous discussion). Each time the chromosome
replicates during production of new cells, the complete chromosome
is not duplicated; a small section at the end of the chromosome is
lost. If it were not for telomeres, this would result in the loss
of important genetic information needed to sustain the cell’s
activity.
Simplified DNA Over time, the
telomere section gets smaller and smaller. There seems to be a
minimum telomere length for healthy cells. If the telomere is
all “used up” the cell can no longer successfully duplicate.
This process has been referred to as the “end
replication problem.” From a biology/genetics perspective
– this is why and how we age: fewer and fewer cells in our body
can replicate themselves. Research in this
area is still in an early phase, as the exact working and role of
telomere is far from fully understood. Though it is probable that
changing telomere lengths will influence the ability of the cell
to continue to replicate, it has not been positively proved that
telomere shortening is indeed the reason for aging rather than a
consequence of it. Much more research
is needed, but the existence of a “life ending” genetic
instruction is surely a strong evidence of a design decision made
by the Creator to limit the age of mankind! Read on about: (5) Exhibit #4: The Ark of Noah
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